주요 연구 분야

혈관성 어지럼; 유전성 신경이과, 신경안과질환; 전정재활치료

연구 내용

본 연구실에서는 혈관성 어지럼, 유전성 신경이과, 신경안과질환의 진단적 기술 개발과 전정재활치료에 역점을 두고 있다. 혈관성 어지럼에서 뇌졸중 감별을 위한 임상적 및 영상학적 지표를 개발하고자 한다. 최근 혈관성 어지럼의 진단에 뇌관류영상이 매우 유용함을 증명하였고, 심장기원 어지럼의 특성을 분석하여 진단 기준을 제시하였다. 다양한 신경이과 및 신경안과적 질환, 특히 간헐성 실조증, 선천성 안진, 메니에르병에 관여하는 유전자 이상을 whole-exome sequencing과 targeted gene sequencing using next generation sequencing (NGS) panel등을 이용하여 연구하고 있고, 최근 한국인에서 다양한 유전자 이상을 발표한 바 있다. 또한, 다양한 전정계 질환에서 Virtual reality를 이용한 새로운 전정재활치료를 개발하고자 한다.   

Selected publications

1. Kim HA, Ahn J, Park HS, Lee SM, Choi SY, Oh EH, Choi JH, Kim JS, Choi KD. Cardiogenic vertigo: characteristics and proposed diagnostic criteria. J Neurol. 2020 Oct 6.

2. Short-Term Central Adaptation in Benign Paroxysmal Positional Vertigo. Choi SY, Lee MJ, Oh EH, Choi JH, Choi KD. Front Neurol. 2020 Apr 21;11:260.

3. Effect of the Epley Maneuver and Brandt-Daroff Exercise on Benign Paroxysmal Positional Vertigo Involving the Posterior Semicircular Canal Cupulolithiasis: A Randomized Clinical Trial. Choi SY, Cho JW, Choi JH, Oh EH, Choi KD. Front Neurol. 2020 Dec 3;11:603541.

4. Choi KD, Choi SY, Choi JH, Kim SH, Lee SH, Jeong SH, Kim HJ, Choi JY, Kim JS. Characteristics of single ocular motor nerve palsy associated with anti-GQ1b antibody. J Neurol. 2019 Feb;266(2):476-479.

5. Choi JH, Oh EH, Park MG, Baik SK, Cho HJ, Choi SY, Lee TH, Kim JS, Choi KD. Early MRI-negative posterior circulation stroke presenting as acute dizziness. J Neurol. 2018 Dec;265(12):2993-3000.

6. Choi KD, Kim JS. Vascular vertigo: updates. J Neurol. 2018 Sep 5.

7. Choi SY, Jang JY, Oh EH, Choi JH, Park JY, Lee SH, Choi KD. Persistent geotropic positional nystagmus in unilateral cerebellar lesions. Neurology. 2018 Sep 11;91(11):1053-1057.

8. Choi JH, Jung JH, Oh EH, Shin JH, Kim HS, Seo JH, Choi SY, Kim MJ, Choi HY, Lee C, Choi KD. Genotype and Phenotype Spectrum of FRMD7-Associated Infantile Nystagmus Syndrome. Invest Ophthalmol Vis Sci. 2018 Jun 1;59(7):3181-3188.

9. Choi KD, Kim JS, Kim HJ, Jung I, Jeong SH, Lee SH, Kim DU, Kim SH, Choi SY, Shin JH, Kim DS, Park KP, Kim HS, Choi JH. Genetic Variants Associated with Episodic Ataxia in Korea. Sci Rep. 2017;7(1):13855.

10. Choi JH, Park MG, Choi SY, Park KP, Baik SK, Kim JS, Choi KD. Acute Transient Vestibular Syndrome: Prevalence of Stroke and Efficacy of Bedside Evaluation. Stroke. 2017;48(3):556-562.

11. Choi KD, Choi SY, Choi JH, Kim SH, Lee SH, Jeong SH, Kim HJ, Choi JY, Kim JS.Characteristics of single ocular motor nerve palsy associated with anti-GQ1b antibody. J Neurol. 2019 Feb;266(2):476-479.

12. Choi KD, Jen JC, Choi SY, Shin JH, Kim HS, Kim HJ, Kim JS, Choi JH. Late-onset episodic ataxia associated with SLC1A3 mutation. J Hum Genet. 2017 Mar;62(3):443-446.